Customization: | Available |
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CAS No.: | 70288-86-7 |
Formula: | C48h74o14 |
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Name: Ivermectin(IVM)
CAS: 70288-86-7
Chemical formula: C48H74O14
Appearance: White or yellowish-Crystalline powder
IVM is a new type of highly efficient semi synthetic antibiotic that kills insects, mites, and nematodes. It belongs to the category of insect neurotoxins and biological penetrating agents. Ivermectin is a new type of broad-spectrum, efficient, and low toxicity antibiotic type antiparasitic drug, which has good repellent effects on both internal and external parasites, especially nematodes and arthropods. But it is ineffective for tapeworms, flukes, and protozoa. The repellent effect of macrolide antiparasitic drugs on nematodes and arthropods is to increase the inhibitory neurotransmitter of Chemicalbook parasites γ- The release of aminobutyric acid (GABA) and the opening of glutamate controlled Cl ion channels enhance the permeability of the nerve membrane to Cl, thereby blocking the transmission of nerve signals, ultimately leading to nerve paralysis and loss of muscle cell contraction ability, leading to parasite death.
Indications of function
This product is a derivative of avermectin, which is an oral semi-synthetic broad-spectrum antiparasitic drug. This product is effective against most (but not all) nematodes of various life cycles; it is effective against microfilariae of Onchocerciasis, but not adults; it is also effective against strongyloides only in the intestinal tract. This product has a selective inhibitory effect. It binds with high affinity to chloride ion channels with glutamate as the valve in nerve cells and muscle cells of non-vertebral animals, resulting in an increase in the permeability of cell membranes to chloride ions, causing nerve cells or muscles. The cells hyperpolarize, paralyzing or dying the parasite. It also interacts with chloride channels of other ligand valves, such as the neurotransmitter g-aminobutyric acid (GABA). The selectivity of this product is due to the absence of glutamate-chloride channels in some mammals and the low affinity of abamectin for mammalian ligand-chloride channels. This product cannot penetrate the human blood-brain barrier. Onchocerciasis and strongyloidiasis and hookworm, roundworm, whipworm, pinworm infection.
Item
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Specification
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Appearance
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White or yellowish-Crystalline powder |
Water %
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≤1.0
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Assay | 95%-102% |
Individual impurities(RRT1.3-1.5)%
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≤2.5
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Sulphated ash% |
≤0.1
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Formamide% | ≤3.0 |
Sum of impurities% | ≤5 |
Dalian Sinobio Chemistry Co.,Ltd was established in 2011 and located in beautiful costal city .We focus on fungicide and water treatment's production and export over 12 years. Sinobio is a group company who has 2 production sites in China: One is in Jiangxi province which produce fungicide such as lsothiazolinon,BIT,Zinc Pyrithione ,etc.Our products can be widely used in the fields of oil-field water injection, pulp and paper making,water treatment,marine paint, wood, plastic leather,paint coating,cosmetics,personal care products, textiles, fiber, building materials,etc. for sterilization,corrosion prevention and mildew prevention.In particular, it has been widely recognized in the application of sterilization,algae killing,scale inhibition and corrosion inhibition of circulating cooling water in petrochemical, power metallurgy and other industrial fields. The other one was located in Gansu province which produce water treatment chemicals such as ATMP, HEDP,THPS,TXP etc .Our company has realized the research and development, production and sales of products and provided a series of services such as water treatment engineering solutions. The products are widely used in electric power,chemical industry, metallurgy, textile,paper making, washing, building mate- rials and other fields. All these products are exported to Europe,America,Russia,Southeast Asia and other parts of the world, and have won the praise of custom. SINOBIO Warmly welcome customers from at home and abroad to cooperate with us for common success. |
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We have more than 20+ years of experience in chemical exhibitors andalways participated in domestic and international exhibitions,such as CPHI, CHEMSPEC, CAC, KHIMIA and so on. Choose SINOBIO Chemistry, we will be your professional chemical raw material supplier. Looking forward to meeting you in our exhibitions.
1. Can I get samples ?
Yes, we can supply specified quantity free sample, you pay for the freight charge only.
2. Which documents do you support?
Normally speaking, our MOQ is 1 standard package. But we can supply free sample for testing before mass order.
4. How can you guarantee the quality of your products?